Today's Signal to Noise Ratio = 14:223

Career stuff
Roy Osherove - Advertise your Tool/Component/Site on ISerializable.com
Ben Reichelt - Best way to ensure processes are followed
via Elis Web - Items of Interest: 2006.04.22 - How to avoid office politics
Chris Bailey - The Greater Sin Is Not Dreaming Big Enough

Web stuff
Scott Guthrie - Always set the "applicationName" property when configuring ASP.NET 2.0 Membership and other Providers and Analyze .NET assemblies using NDepend

Other stuff
Ayende @ Blog - Book Review: Data Binding with Windows Forms 2.0: Programming Smart Client Data Applications with .NETand
Alex Hoffman - Books and an Update to Fritz Onion's Classic
Joe Duffy - Multi-core workloads
Roy Osherove - My Tech-Ed Talk: Deep Reflection - What's new & Hot in Reflection 2.0 … sounds like a great session ...
Junfeng Zhang - Sxs --- Activation Context, Binding, Policy and Probing

.Net Community stuff
Korby Parnell - DasTrip

Debugging stuff
Mike Stall - Felice Pollano: Integrating a debugger into Reflector and Using a Profiler for inspection